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Home > Health and Fitness > Nutrition > Benefits of Vitamin E and Vitamin K
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Benefits of Vitamin E and Vitamin K
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Vitamin E (Tocoferol): Vitamin E is the generic name for a group of
closely related and naturally occurring fat-soluble compounds, the
tocopherols. Of these, alpha-tocopherol is biologically the most
potent.
Sources: Vitamin E is widely distributed in foods. By far the richest
sources are vegetable oils, cotton seed, sunflower seed, egg yolk and
butter. Foods rich in poly unsaturated fatty acids are also rich in
vitamin E.
Daily requirements: The usual plasma level of vitamin E in adults is
between 0.8 and 1.4 mg per 100 ml (37). While there is no doubt that
man requires tocopherol in his diet, there is no clear indication of
dietary deficiency. The role of vitamin E at the molecular level is
little understood. The current estimate of Vitamin E requirement is
about 10 mg per day adult.
Recently the cytotoxic of vitamin E on human lymphocytes in vitro at
high concentrations has been reported. This being so, caution should
exercised against the mega-dose consumption of vitamin E is clinical
practice.
Vitamin K: Vitamin K occurs in at least two major forms—vitamin K1 and
vitamin K2. Sources: Vitamin K 1 is found mainly in fresh green
vegetables particularly dark green ones, and some fruits. Cow’s milk is
a richer source (60mcg/L) of vitamin K than human milk (15mcg/L).
Vitamin K2 is synthesized by the intestinal bacteria, which usually
provide an adequate supply in man. Long-term administration of
antibiotic does for more than a week may temporarily suppress the
normal intestinal flora, (a source of vitamin K2) and may cause a
deficiency of vitamin K. Vitamin K is stored in the liver. The role of
vitamin K is to stimulate the production and/or the release of certain
coagulation factors. In vitamin K deficiency, the prothrombin content
of blood is markedly decreased and the blood clotting time is
considerably prolonged.
Daily requirements: The vitamin K requirement of man is met by a
combination of dietary intake and microbial synthesis in the gut. The
daily requirement for man appears to be about 0.03mg/kg for the adult.
Newborn infants tend to be deficient in vitamin K due to minimal stores
of prothrombin at birth and lack of an established intestinal flora.
Soon after birth, all infant or those at increased risk should receive
a single instamuscular does of a vitamin K preparation (0.1-0.2 mg of
menadione sodium bisufite or 0.5 mg of vitamin K1) by way of
prophylaxis. |
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